Third-Party Tested ≥98% HPLC Purity — USA Shipped

Tesamorelin 5mg - Research Peptide
Metabolic & Incretin 5mg

Tesamorelin 5mg

$40.50 In Stock

Synthetic GHRH analogue studied for visceral fat reduction and metabolic health.

$40.50
1
≥98%
HPLC Purity
COA
Included
USA
Based Supplier

Description

Synthetic GHRH analogue studied for visceral fat reduction and metabolic health.

Tesamorelin is a synthetic analogue of growth hormone-releasing hormone (GHRH) consisting of the 44-amino acid human GHRH sequence with a trans-3-hexenoic acid modification at the N-terminus. It acts by binding to GHRH receptors on anterior pituitary somatotroph cells, stimulating pulsatile growth hormone (GH) release while preserving the natural hypothalamic-pituitary feedback axis. Beyond lipodystrophy research, studies published in Annals of Neurology (Baker et al., 2012) suggest tesamorelin may improve cognitive function in older adults with mild cognitive impairment by modulating IGF-1 levels in the central nervous system. Compared to direct GH use, tesamorelin preserves physiological GH pulsatility rather than creating supraphysiological sustained GH levels, which research indicates may reduce the risk of insulin resistance associated with exogenous GH. Additional preclinical work has explored its role in peripheral nerve regeneration models. The lyophilized powder should be stored at controlled room temperature (20-25C) or refrigerated; reconstitute with sterile water and use within 24 hours or refrigerate for up to 14 days. This peptide is studied by endocrinology research labs, HIV metabolism centers, and neuroscience institutions investigating GH-IGF-1 axis modulation.

This product is supplied as a lyophilized powder and is intended for laboratory and research use only. Not for human consumption. Each vial contains 5mg of research-grade material.

Read the full Tesamorelin research guide

Research Applications

  • HIV-associated lipodystrophy and visceral fat reduction
  • Peripheral nerve regeneration
  • Cognition and neurodegeneration models
  • Cardiovascular health through metabolic markers

Specifications

Size
5mg
Purity
≥98% (HPLC)
Form
Lyophilized Powder
Molecular Formula
C223H370N72O69S
Molecular Weight
5195.91 g/mol
CAS Number
901758-09-6

Storage & Handling

  • Long-term storage: -20°C in a sealed, light-protected container
  • Short-term storage: 2-8°C (refrigerated) for up to 30 days
  • Reconstituted: Store at 2-8°C and use within 30 days
  • Avoid: Repeated freeze-thaw cycles, direct sunlight, and moisture exposure
  • Reconstitution: Use bacteriostatic water or sterile water for injection

Frequently Asked Questions

What is Tesamorelin and how does it work?
Tesamorelin is a synthetic analogue of growth hormone-releasing hormone (GHRH) with a trans-3-hexenoic acid modification at the N-terminus. It binds to GHRH receptors on pituitary somatotroph cells, stimulating the pulsatile release of endogenous growth hormone. This mechanism has been studied for its downstream effects on IGF-1 levels, visceral adipose tissue metabolism, and hepatic lipid profiles.
What research has been done on Tesamorelin?
Tesamorelin has been studied in multiple clinical trials for HIV-associated lipodystrophy, where it received FDA approval (as Egrifta). Published research in the Journal of Clinical Endocrinology & Metabolism demonstrated significant reductions in visceral adipose tissue. Additional studies have explored its effects on peripheral nerve regeneration, mild cognitive impairment in aging populations, and non-alcoholic fatty liver disease biomarkers.
How does Tesamorelin compare to Sermorelin?
Both tesamorelin and sermorelin are GHRH analogues, but tesamorelin's trans-3-hexenoic acid modification provides greater resistance to enzymatic degradation, resulting in higher bioavailability and more potent GH release per exposure in research models. Sermorelin is a shorter fragment (amino acids 1-29 of GHRH), while tesamorelin includes the full 44-amino acid sequence with the N-terminal modification.

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Research Use Only. This product is not intended for human consumption, therapeutic use, or diagnostic purposes. All peptides sold by Elyte Peptides are strictly for in-vitro research and laboratory use. By purchasing, you agree to use this product in compliance with all applicable laws and regulations.