HCG: Dosage, Benefits & Research Guide
What is HCG?
Human chorionic gonadotropin is a glycoprotein hormone that mimics luteinizing hormone by binding the LH/hCG receptor on Leydig and granulosa cells. In research settings it is used as a tool to study steroidogenesis, gonadal function, and the hypothalamic-pituitary-gonadal axis, including models of testosterone production and ovulation induction pathways. Because of its long half-life and potent receptor activity, it is a common reference agonist in reproductive endocrinology research. Supplied as a lyophilized powder for in-vitro and laboratory research use only; not for human or veterinary use.
HCG Research Applications
In published and preclinical research, HCG has been studied across the following areas:
- LH/hCG receptor signaling research
- Steroidogenesis and gonadal function studies
- Reproductive endocrinology models
- HPG-axis research
HCG in Research: Reconstitution & Study Concentrations
HCG is supplied as a lyophilized powder. For laboratory research it is reconstituted with bacteriostatic or sterile water; the solvent volume sets the working concentration. Published studies select concentrations specific to the assay or model system — there is no human dose, as HCG is not approved for human use. Researchers should reference the primary literature for the model in question and document the exact lot COA.
Worked example: a 10,000 IU vial reconstituted with 2 mL of bacteriostatic water yields 5000.00 mg/mL.
Open the reconstitution calculator