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Ipamorelin 10mg - Research Peptide
Body Composition 10mg

Ipamorelin

$79.00 In Stock

Highly selective synthetic pentapeptide GH secretagogue for research.

≥98%
HPLC Purity
COA
Included
USA
Based Supplier

Description

Highly selective synthetic pentapeptide GH secretagogue for research.

Ipamorelin is a synthetic pentapeptide (Aib-His-D-2Nal-D-Phe-Lys-NH2) that acts as a selective agonist of the growth hormone secretagogue receptor (GHS-R1a/ghrelin receptor). Its mechanism involves binding the ghrelin receptor on anterior pituitary somatotrophs to trigger calcium influx and GH granule exocytosis. What distinguishes ipamorelin from earlier ghrelin mimetics is its remarkable selectivity: clinical studies by Raun et al. (European Journal of Endocrinology, 1998) demonstrated that ipamorelin stimulates GH release in a dose-dependent manner without significantly affecting cortisol, prolactin, FSH, LH, or TSH levels, even at high doses. This selectivity profile makes it one of the cleanest GH secretagogues available for research. In bone metabolism research, Anderson et al. (Bone, 2001) showed that ipamorelin administration in ovariectomized rat models increased bone mineral content and bone formation markers, suggesting anabolic effects on skeletal tissue independent of IGF-1 elevation. The peptide has also been studied in post-operative recovery models, where it demonstrated prokinetic effects on gastric motility. Compared to GHRP-6 and GHRP-2, which also activate the ghrelin receptor but additionally stimulate appetite and affect cortisol/prolactin levels, ipamorelin provides a more isolated GH response. Compared to hexarelin, another GHRP, ipamorelin shows less desensitization with repeated dosing. Store lyophilized powder at -20C; reconstitute with bacteriostatic water and refrigerate at 2-8C for up to 28 days. Ipamorelin is investigated by endocrinology labs, bone metabolism research centers, orthopedic research departments, and gastrointestinal motility researchers.

This product is supplied as a lyophilized powder and is intended for laboratory and research use only. Not for human consumption. Each vial contains 10mg of research-grade material.

Research Applications

  • Bone metabolism and structural integrity
  • Muscle preservation and anabolism
  • Glucose regulation studies
  • Post-operative recovery research

Specifications

Size
10mg
Purity
≥98% (HPLC)
Form
Lyophilized Powder
Molecular Formula
C38H49N9O5
Molecular Weight
711.87 g/mol
CAS Number
170851-70-4

Storage & Handling

  • Long-term storage: -20°C in a sealed, light-protected container
  • Short-term storage: 2-8°C (refrigerated) for up to 30 days
  • Reconstituted: Store at 2-8°C and use within 30 days
  • Avoid: Repeated freeze-thaw cycles, direct sunlight, and moisture exposure
  • Reconstitution: Use bacteriostatic water or sterile water for injection

Frequently Asked Questions

What is Ipamorelin and how does it work?
Ipamorelin is a synthetic pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH2) that acts as a highly selective agonist of the ghrelin receptor (GHS-R1a). Unlike other GH secretagogues, ipamorelin stimulates growth hormone release from the pituitary with minimal effects on ACTH, cortisol, prolactin, or appetite. This selectivity makes it a valuable tool for studying GH-specific signaling pathways without confounding hormonal variables.
What research has been done on Ipamorelin?
Research published in the European Journal of Endocrinology demonstrated ipamorelin's selective GH-releasing properties with a favorable safety profile. Studies in Growth Hormone & IGF Research showed dose-dependent GH secretion without significant desensitization over repeated administrations. Additional research has explored its effects on bone mineral density (orthopedic surgery recovery models), post-operative ileus, and glucose metabolism.
How does Ipamorelin compare to GHRP-2 and GHRP-6?
Ipamorelin is the most selective of the three GH secretagogues. GHRP-6 strongly stimulates hunger and elevates cortisol and prolactin. GHRP-2 is moderately selective with some cortisol and prolactin effects. Ipamorelin releases GH in a dose-dependent manner with negligible impact on other pituitary hormones, making it the preferred tool compound for research requiring clean GH signaling data.
What is the recommended reconstitution protocol for Ipamorelin?
For this 10mg vial, reconstitute with 2mL of bacteriostatic water for a 5mg/mL solution. Ipamorelin has a moderate molecular weight (711.87 g/mol) and typically dissolves within 2-3 minutes. Direct water slowly along the vial wall. Store reconstituted solution at 2-8°C and use within 30 days.
What purity testing is performed on Ipamorelin?
Each batch is analyzed by HPLC for minimum 98% purity. Molecular identity is verified by mass spectrometry against the expected 711.87 g/mol. Amino acid analysis confirms the correct sequence, and chiral analysis verifies the D-amino acid configurations. Endotoxin testing and residual solvent analysis are performed. A Certificate of Analysis (COA) accompanies every batch.

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Research Use Only. This product is not intended for human consumption, therapeutic use, or diagnostic purposes. All peptides sold by Elyte Peptides are strictly for in-vitro research and laboratory use. By purchasing, you agree to use this product in compliance with all applicable laws and regulations.